Track 1- Down syndrome

A genetic disorder where an abnormal cell division takes place and results in full or partial copy of chromosome 21 also known as trisomy 21 which causes an underdeveloped mental and physical features.

Track 2- Down syndrome signs and symptoms

Person with Down syndrome have physical as well as intellectual disabilities the also have poor immune system and their physical and mental development  is slow as compared to the normal people, They have a huge risk of other health problems such as epilepsy, thyroid diseases, congenital heart disease, leukaemia, tumour and blood cancer.

Track 3- Down syndrome and Epilepsy

It is a neurological disorder, in which nerve cell activity in the brain is disturbed, causing seizures. Epilepsy may occur as a result of a genetic disorder or an acquired by brain injury.

Track 4- Congenital Heart Disease in Down syndrome

Congenital heart disease among Down syndrome is around 40% and above 80% of people have ventricular septal defect, atrioventricular septal disease as well as mitral valve problem.

Track 5- Cancer in Down syndrome

People with Down syndrome have a risk of developing cancer from germ cells which can be blood or non-blood related. The risk of testicular cancer and blood cancer is more which also includes acute lymphoblastic leukaemia (ALL) and acute megakaryoblastic leukaemia (AMKL).

Track 6- Endocrinology in Down syndrome

20-50% of people with Down syndrome suffer with thyroid gland problem; congenital hypothyroidism is the most common form of low thyroid within the individual resulting in Type 1 diabetes mellitus, autoimmune hypothyroidism and Grave’s disease.

Track 7- Fertility

Females with Down syndrome are fertile and do ovulate but also they get earlier menopause, about 35-50% of Down syndrome mothers gave birth to children have trisomy21 and other disabilities. Whereas males with Down syndrome have poor fertility as the suffer problem with sperm production and development and generally do not father children.

Track 8- Chromosomal Translocation and Trisomy 21

Down syndrome is caused by having three copies of genes on chromosome 21 also known as mosaic Down syndrome which can also give rise to Robertsonian translocation, isochromosome or ring chromosome, these contain an additional genomic material from chromosome 21.

Track 9- Epigenetics and its mechanism

The study of heritable phenotypic changes that involve modification in the DNA sequence is called epigenetics such as DNA methylation and histone modification.

Track 10- Screening and Diagnosis

Down syndrome can be screened by amniocentesis or chronic villus sampling, blood testing, ultrasound (measures nuchal translucency), Quad screening (measures the maternal serum alpha-fetoprotein, unconjugated estriol, HCG and inhibin-A) Cell-free foetal DNA (blood sample of the foetus is collected by venipunture and DNA analysis is done)

Track 11- Down syndrome management and Prognosis

Down syndrome management can be done by health screening in a systematic way and cognitive development by hearing aids, Speech therapy, sign language, augmentive and alternative communication methods.

Down syndrome also depends upon the medical problem faced and complications, earlier children born with Down syndrome had a life span of 9 years but now due to the advance medical technologies and quality of life have increased their life span up to 55 years and many lived even longer.

Track 12- Down syndrome Prevention

Down syndrome can be prevented by consulting a genetic counsellor before becoming pregnant and discussing about the risk factor but ultimately the condition cannot be prevented.

Track 13- Autism or Autism spectrum disorder

Autism is caused due to both the combination of genetics and environment, Autism is highly variable neurodevelopmental disorder whose symptoms first appears during infancy, this is distinguished by a traid of symptoms like trouble with social interaction, impaired communication, restricted interests, repetitive behaviour.

Track 14- Autism and its causes

Autism has a strong genetic basis it is explained more by mutation, Exposure to air pollution during pregnancy, especially heavy metals and particulates, may increase the risk of autism. Maternal nutrition inflammation during preconception and pregnancy influences foetal neurodevelopment.

Track 15- Screening and Diagnosis of Autism

Since there is no medical test like a blood test, etc. to diagnose the disorders. Doctors look at the child's behaviour and development to make a diagnosis.

Track 16- Autism Management and Prevention.

Autism management can be done by health screening in a systematic way and cognitive development by hearing aids, Speech therapy, special education, augmentive and alternative communication methods and services should be carried out by behaviour analyst, speech pathologist and licensed psychologist.

Track 17- Cerebral palsy and its cause

It’s a congenital disorder of movement, muscle tone or posture, cerebral palsy affects body movement and muscle coordination, reflex, balance and it is caused due to brain injury or brain malformation that occurs while the brain is at its developing stage i.e., before, during, or after birth.

Track 18- Cerebral palsy diagnosis and management

Cerebral palsy is diagnosed by checking family history and physical examination, early diagnosis and intervention works wonders in case of managing cerebral palsy as it is a developmental disability. There are many preventive interventions that have been investigated. The method Electronic foetal monitoring helps to prevent cerebral palsy.

Conference series LLC LTD is hosting Down syndrome 2020 inviting all the participants from all over the globe to the World Congress on Down syndrome, Autism & Cerebral Palsy, scheduled during July 22-23, 2020 at Melbourne, Australia with a theme “Let’s stand up for Down syndrome and focus on abilities not disabilities”.

Down Syndrome is a genetic disorder where an abnormal cell division takes place and results in full or partial copy of chromosome 21 also known as Trisomy 21 and Mongolism which causes an underdeveloped mental and physical features. Person with Down syndrome have physical as well as intellectual disabilities the also have poor immune system and their physical and mental development  is slow as compared to the normal people, They have a huge risk of other health problems such as epilepsy, thyroid diseases, congenital heart disease, leukaemia, tumour and blood cancer.

Global sub normality market is rising bit by bit with a considerable CAGR within the forecast amount of 2019-2026. The high prevalence of sub normality is increasing governmental funding for development of novel therapies and rising awareness regarding the malady area unit the most important drivers for the market growth.

Down Syndrome - medicine Forecast-2027' report delivers Associate in Nursing in-depth understanding of the malady, historical & forecasted medicine still because the market trends of Down's syndrome within the u. s., EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan. The Down's syndrome market report offers the thorough understanding of the Down's syndrome by as well as details like malady definition, classification, symptoms, etiology, pathophysiology, diagnostic trends. It conjointly provides treatment algorithms and treatment pointers for Down's syndrome within the United States of America, Europe, and Japan.

According to this analysis, the current cases of backwardness were 541,538 in 2016 in seven millimetres and, are anticipated to extend throughout the study amount i.e., 2016-2027. Among 7MM, U. S. accounts for the best current cases of backwardness with 258,502 current cases in 2016. In 7MM, males had the best current cases of DS as compared to females in 2016. This trend is anticipated to extend throughout the study amount

Down syndrome market is expected to grow during the forecasted period of 2018-2027 owing to the launch of few drugs. Down syndrome therapeutics market has seen a 7MM sale of USD 1621.40 Million from 2016.

World Congress on Down Syndrome, Autism & Cerebral Palsy scheduled during July 22-23, 2020 at Melbourne, Australia

The conference “World Congress on Down Syndrome, Autism & Cerebral Palsy” was successfully completed which scheduled during October 21-22, 2019 at Tokyo, Japan with a theme “Exploring the Challenges and Excellence in Down Syndrome and Autism”. The conference was initiated with the honorable presence of the Keynote forum. The list includes:

• Title: Depression-like Behavior and Hypomotility in Acutely Forced Swimming Rat Improved by Prokinetic Meranzin Hydrate from Chaihu-Shugan-San via Ghrelin and Neurocircuitry

          Xi Huang, Nanjing University of Chinese Medicine, China

• Title: A Study on the Perceptions of Parents on Savant Skills of Individuals with ASD

           Eunice Tan Meng Yin, Singapore University of Social Sciences, Singapore

• For More details visit: https://downsyndrome-autism.conferenceseries.com/scientific-program
• Book mark your calendars; we are hoping to see you soon!
• Let us meet again @ Down Syndrome 2020