Molecular Genetics of Down Syndrome
The genetic material, known as genes, carries the codes responsible for all our inherited characteristics. Genes are grouped along rod-like structures called chromosomes. Normally, the nucleus of each cell contains 23 pairs of chromosomes, half of which are inherited from each parent. In individuals with Down syndrome, however, the cells usually contain 47, not 46, chromosomes; the extra chromosome is the 21st. This excess genetic material, in the form of additional genes along chromosome 21, results in Down syndrome. The extra 21st chromosome is detected by using a procedure called a karyotype
- Genes Within the Down Syndrome
- Acute Megakaryoblastic Leukemia of Down Syndrome
- Transient Myeloproliferative Disorder of Down Syndrome
- Atrioventricular Septal Defects of Down Syndrome
- Acute Lymphoblastic Leukemia of Down Syndrome
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